Learn about Vitamin U (S-methylmethionine), a compound found in cabbage and cruciferous vegetables traditionally associated with digestive wellness.
What is Vitamin U?
Vitamin U is the common name for S-methylmethionine (SMM) – a naturally occurring compound found in cabbage, broccoli, and other cruciferous vegetables.
It is not officially classified as a vitamin, but the name comes from early research linking it to “ulcer” healing, which is where the “U” originated.
What Vitamin U is known for:
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Supporting gastric mucosal protection
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Supporting the stomach’s natural repair mechanisms
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Traditionally associated with cabbage juice therapy for stomach discomfort
Vitamin U has been studied intermittently since the 1940s, but modern, real-world data on symptom experience is limited, especially outside of clinical hospital settings.
That’s the gap we’re exploring.
S-methylmethionine (Vitamin U)
A special-release supplement developed for exploratory testing and educational purposes.
Directions: Take 1 capsule one or twice a day with food, or as directed by a healthcare professional.
Active ingredient: S-Methylmethionine (as S-methylmethionine sulfonium chloride) – 500 mg
Other ingredients: Vegetable capsule
Free from artificial colors, flavors, and preservatives.
Please contact us if you are interested in trying Vitamin U.
Below are studies and references for those who wish to explore further:
Key historical studies
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Cheney, G. (1949) Rapid Healing of Peptic Ulcers in Patients Receiving Fresh Cabbage Juice
Stanford University School of Medicine
→ One of the first studies linking cabbage-derived compounds to ulcer healing. -
Cheney, G. (1952) Vitamin U therapy of peptic ulcer
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Drozdov (2023) Effect of 6-month S-methylmethionine intake on the quality of life and dyspepsia symptoms in patients with chronic gastritis
Related nutritional & mechanistic research
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Research on gastric mucosal protection
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Studies on sulfur-containing amino acid derivatives
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Research into dietary cabbage juice and stomach lining regeneration
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Gut-brain axis literature connecting gastric inflammation with anxiety and mood symptoms
Other potential health benefits
Beyond stomach lining support, S-methylmethionine (Vitamin U) has been explored for a few additional areas of interest, primarily due to its role in methylation and cellular protection.
Preliminary and historical research suggests it may:
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Support cellular repair and regeneration
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Contribute to liver support through methyl donation pathways
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Help protect tissues from oxidative stress
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Play a role in gut–brain signaling, which may indirectly influence stress-related digestive symptoms
It’s important to note that these potential benefits are not well-established in modern clinical trials, and individual responses vary.